NetBackup Flex Scale tuning
Recommended # of VMs per ESXi for VMware backup
This parameter is set for VMware workloads. When the number of VMs is less than or equal to two per ESXi host, the performance is linear. Set this value to 5 on the ESXi host.
Latency between sites during replication
Network latency between primary and secondary site should be minimal. The recommended value is less than 2 ms. You must have a reliable network with minimal packet drops and reordering. There should not be a Network Address Translation (NAT) based firewall between the source and the target sites.